Preclinical Inhalation in Vivo and In Vitro Services – Tailored to Your Project Needs

Optimization of Aerosol Delivery for Efficacy and Toxicology Studies

  • Particle size measurement
  • Deposition prediction
  • Excipient evaluation
  • Optimization of concentration/exposure

Administration Techniques

  • Intranasal
  • Intratracheal instillation
  • Wet and dry aerosol
  • Nose only exposure
  • Whole body exposure

Efficient and Flexible Expertise with Extensive Experience of Designing, Performing and Reporting Preclinical Studies

In Vitro

  • A wide range of cell-based assays for mode-of-action and efficacy/potency studies, including ALI (Air-Liquid Interface) cultures
  • Biochemical assays
  • Biomarker analysis
  • Protein engineering and genotyping
  • In vitro bioavailability (CaCo and CaLu)

In Vivo

  • Client customized efficacy (PD) models within e.g. inflammation (respiratory, CV, GI), oncology, wound  infection and surgical intervention.
  • Pharmacokinetic (PK) studies
  • PK/PD relationship and dose prediction
  • Small animal imaging (optical, MRI, CT and PET)
  • Lung irritancy
  • Inhalation toxicology packages (in collaboration)

Consultancy Services with Emphasis on Pharmacology,
Translational Science and Business Development


  • Strategic project plans incl. Target Product Profile (TPP)
  • Preclinical study design; study protocols
  • Preclinical inhalation expertise
  • Regulatory preclinical development plans and documentation

Translational Science

  • Translational medicine plans
  • Biomarker plan; identification and implementation for preclinical and clinical use

Business Development

  • Market research and evaluation
  • Evaluation of project ideas and projects
  • Business plans and business cases
  • Advice on in & out-licensing incl. presentation material
  • Advice on early financing

Download the pdf MVIC_Preclinical Inhalation In Vivo & In Vitro Services

Preclinical inhalation in vivo and in vitro services
Preclinical inhalation in vivo and in vitro services