Drug Discovery & Translational Science

Complete lead discovery and optimization projects
Medicinal chemistry – design & synthesis of small molecules
Compound optimization for inhalation – lung retention and metabolic profile
Fragment-based screening for new chemical starting points
Peptide chemistry – design & synthesis
Radio isotope chemistry
NMR spectroscopy
Bioanalysis by LC-MS/MS
Physicochemical profiling and in vitro ADME
Assay development and screening (biochemical and cell-based assays – development & screening)
Transition from preclinical in vitro studies to concept testing in patients
Biomarkers
Pharmacology
Pharmacodynamics (PD)
Pharmacokinetics (PK)
Toxicology support